Asia Pacific Vascular Biology Organization Conference 2017

Conference Program

Nov 18-19, 2017    
State Key Laboratory of Ophthalmology    
Zhongshan Ophthalmic Center    
Jinsui Road 7, Pearl river new city, Guangzhou, China

— Nov 18, 2017 —

Morning session 1:Vascular biology of atherosclerosis

Chairs: Napoleone Ferrara (UCSD) and Xuri Li (ZOC)

  • 8:20-8:30, Yizhi Liu: Opening remark
    ZOC, SYSU, China

  • 8:30-8:55, Ira Tabas: Defective inflammation resolution in atherosclerosis: mechanisms and therapeutic opportunities
    Columbia University, USA

  • 8:55-9:00, Discussion

  • 9:00-9:25, Martin A. Schwartz: Endothelial fluid shear stress responses in vascular remodeling and atherosclerosis
    Yale University School of Medicine, USA

  • 9:25-9:30, Discussion

  • 9:30-9:50, Pei-Yu Chen: TGFβ suppresses the multilineage potential of adult smooth muscle cells in aortic disease
    Yale University School of Medicine, USA

  • 9:50-9:55, Discussion

  • 9:55-10:10, Hui Huang: lL 18 accelerated vascular calcification in hypertensive patients
    Sun Yat-sen Memorial Hospital, SYSU, China

  • 10:10-10:15, Discussion

               Coffee break 15 min            
Morning session 2:Regulation of vascular permeability and ocular neovascularization

Chairs: Xiao-Li Tian (Nanchang University), Zhongwei Cao (Sichuan University) and Michael Simons (Yale)

  • 10:30-10:50, Dietmar Vestweber: Regulation of endothelial junctions during leukocyte diapedesis
    Max Planck Institute for Molecular Biomedicine, Germany

  • 10:50-10:55, Discussion

  • 10:55-11:15, Christiana Ruhrberg: Vascular permeability regulation by VEGF isoforms
    University College London, UK

  • 11:15-11:20, Discussion

  • 11:20-11:40, Tatiana V Byzova: The role of innate immune cells in vascular patterning
    Cleveland Clinic, USA

  • 11:40-11:45, Discussion

  • 11:45-12:05, Martin Friedlander: Stemming vision loss with stem cells and a little help from VEGF, VHL and HIF
    The Scripps Research Institute, USA

  • 12:05-12:10, Discussion

  • 12:10-12:20, Yuqiang Wang: Novel therapy for diabetic retinopathy
    Jinan University, China

  • 12:20-12:25, Discussion

  • Novartis Satellite Conference (lunch provided)

    Chair: Xuri Li (ZOC)

  • 12:30-13:30 PM, The treatment of wAMD

Afternoon session 1:Vascular signaling

Chairs: Martin A. Schwartz (Yale), Tatiana V Byzova (Cleveland Clinic) and Yuqiang Wang (Jinan University)

  • 14:00-14:08, Jia Li: Targeting VE-cadherin normalises endothelium in tumours and cerebral cavernous malformation lesions
    Centenary Institute, Australia

  • 14:08-14:10, Discussion

  • 14:10-14:22, Neil Lagali: Inflammation and angiogenesis in the cornea: insights from genome-wide analysis and anti-inflammatory therapies
    Linköping University, Sweden

  • 14:22-14:25, Discussion

  • 14:25-14:45, Xuri Li: Novel functions of VEGF-B in regulation the FGF pathway
    ZOC, SYSU, China

  • 14:45-14:50, Discussion

  • 14:50-15:02, Luyang Yu: SUMOylation negatively regulates angiogenesis by targeting endothelial NOTCH signaling

    Zhejiang University, China

  • 15:02-15:05, Discussion

  • 15:05-15:20, Lasse Jensen: Zebrafish models for ocular neovascularization provide new opportunities for understanding vascular pathology related to eye disease
    Linköping University, Sweden

  • 15:20-15-25, Discussion

  • 15:25-15:40, Xiao-Li Tian: AGGF1, a novel vascular protector
    Nanchang University, China

  • 15:40-15:45, Discussion

               Coffee break 15 min            
Afternoon session 2:Frontiers of vascular biology

Chairs: Luyang Yu (China), Christiana Ruhrberg (UCL) and Jing Li (GUCM)

  • 16:00-16:12, Zhongwei Cao : Checkpoint decisions made by subverted vascular niche transform indolent tumor cells into chemoresistant cancer stem cells

    Sichuan University, China

  • 16:12-16:15, Discussion

  • 16:15-16:40, Karen Hirschi: Regulation of endothelial cell fate
    Yale University School of Medicine, USA

  • 16:40-16:45, Discussion

  • 16:45-16:57, Feng Zhang: Lacteal junction zippering prevents diet-induced obesity
    Yale University School of Medicine, USA

  • 16:57-17:00, Discussion

  • 17:00-17:25, Kenneth Walsh: Clonal hematopoiesis and cardio-metabolic disease: new mechanisms, new therapeutic opportunities
    Boston University School of Medicine, USA

  • 17:25-17:30, Discussion

  • 17:30-17:55, Ralf H. Adams: Organ-specific specialization and functional heterogeneity of endothelial cells
    Max Planck Institute for Molecular Biomedicine, Germany

  • 17:55-18:00 PM, Discussion

— Nov 19, 2017 —

8:15, All-together photo in front of the main entrance of the SKLO building    

Morning session 1:Vascular Metabolism

Chairs: Ralf H. Adams (Max Planck Institute) and Raghu Kalluri (MD Anderson Cancer Center)            

  • 8:30-8:55, Peter Carmeliet : Angiogenesis revisited: role and (therapeutic) implications of endothelial metabolism

    VIB Center for Cancer Biology, Belgium

  • 8:55-9:00, Discussion

  • 9:00-9:25, Massimo M. Santoro: Redox metabolism in blood vessels
    University of Turin, Italy

  • 9:25-9:30, Discussion

  • 9:30-9:55M, Michael Potente: Metabolic regulation of endothelial growth and quiescence
    Max Planck Institute for Heart and Lung Research, Germany

  • 9:55-10:00, Discussion

  • 10:00-10:25 AM, Michael Simons: Metabolic control of vascular growth
    Yale University School of Medicine, USA

  • 10:25-10:30 AM, Discussion

               Coffee break 15 min            
Morning session 2:Angiogenesis in metabolic diseases and development

Chairs: Karen Hirschi (Yale) and Zhongjun Zhou (Hong Kong)

  • 10:45-11:10, Yihai Cao: Angiogenesis in cancer and metabolic disease

    Karolinska Institute, Sweden

  • 11:10-11:15, Discussion

  • 11:15-11:30, Jing Li: Mechanosensitive calcium ion channel Piezo1 in vascular biology
    Guangzhou University of Chinese Medicine, China

  • 11:30-11:35, Discussion

  • 11:35-11:50, Guang Wang: Ethanol exposure leads to disorder of blood vessel development in early chick embryo

    Jinan University, China

  • 11:50-11:55, Discussion

  • 11:55-12:10, Xiaoqiang Yao: Mechanosensitive TRP channels in cardiovascular system

    The Chinese University of Hong Kong, Hong Kong, China

  • 12:10-12:15, Discussion

Afternoon session 1:Frontiers of translational research

Chairs: Yihai Cao (Karolinska Institute) and Kenneth Walsh (Boston University)

  • 13:45-14:00, Hongye Sun : Global genomic data platform empowering drug discovery and clinical research

    WuXi NextCODE Genomics Inc, China

  • 14:00-14:05, Discussion

  • 14:05-14:30, Napoleone Ferrara: Therapeutic targeting of VEGF-A and other pro-angiogenic mediators

    UC San Diego Moores Cancer Center, USA

  • 14:30-14:35, Discussion

  • 14:35-15:00, Jan Kitajewski: Notch-mediated gene regulation promotes angiogenesis by diverse mechanisms

    University of Illinois at Chicago, USA

  • 15:00-15:05, Discussion

  • 15:05-15:25, Junjian Liu: Developing anti-angiogenesis drugs in China
    Innovent Biologics (Suzhou) Co, Inc, China

  • 15:25-15:30, Discussion

  • 15:30-15:42, Feng Han: Targeting the P2RX 7 pathway for neurovascular protection in septic encephalopathy
    Zhejiang University, China

  • 15:42-15:45, Discussion

               Coffee break 15 min            
Afternoon session 2:Emerging vascular sciences

Chairs: Jan Kitajewski (University of Illinois at Chicago), Michael Potente (Max Planck Institute) and Jingxuan                Pan (ZOC)

  • 16:00-16:15, Jincai Luo : VEGF receptor 2 regulates vascular homeostasis and inflammation via endothelial exocytosis

    Peking University, China

  • 16:15-16:20, Discussion

  • 16:20-16:45, Zhongjun Zhou: MT1-MMP suppresses corneal lymphangiogenesis
    The University of Hong Kong, Hong Kong, China

  • 16:45-16:50, Discussion

  • 16:50-17:05, Bi-Sen Ding: Editing of hematopoietic-vascular niche to stimulate organ regeneration and bypass fibrosis
    Sichuan University, China

  • 17:05-17:10, Discussion

  • 17:10-17:30, Yoshiaki Kubota: Cell-to-cell communication in retinal vascular development
    Keio University School of Medicine, Japan

  • 17:30-17:35, Discussion

  • 17:35-17:55, Raghu Kalluri: Functional contribution of vascular heterogeneity in organotropic metastasis
    University of Texas MD Anderson Cancer Center, USA

  • 17:55-18:00, Discussion